Differential Transcription of SOCS5 and SOCS7 in Multiple Sclerosis Patients Treated with Interferon Beta or Glatiramer Acetate

The participation of proinflammatory cytokines in the progression of Multiple Sclerosis (MS) has been well documented. Cytokines activate the JAK-STAT pathway, in which the suppressors of cytokine signaling (SOCS) exert a negative feedback. This paper analyzes the levels of SOCS5 and SOCS7 transcrip...

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Main Authors: Emmanuel Rojas-Morales, Gerardo Santos-López, Samuel Hernández-Cabañas, Raúl Arcega-Revilla, Nora Rosas-Murrieta, Carolina Jasso-Miranda, Elie Girgis El-Kassis, Julio Reyes-Leyva, Virginia Sedeño-Monge
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-12-01
Colecção:International Journal of Molecular Sciences
Assuntos:
multiple sclerosis
jak-stat
socs5
socs7
ifn-<i>β</i>
glatiramer acetate
Acesso em linha:https://www.mdpi.com/1422-0067/21/1/218
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