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Influenza a virus antagonizes type I and type II interferon responses via SOCS1-dependent ubiquitination and degradation of JAK1
Abstract Background Although influenza A virus (IAV) employs diverse strategies to evade IFN responses by inhibiting the synthesis of IFN, how IAV regulates signaling downstream of IFN is incompletely understood. Methods In this study, we used Western blot-based protein analysis coupled with RT-qPCR...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-06-01
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| Colecção: | Virology Journal |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12985-020-01348-4 |
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