Effects of Eph/ephrin signalling and human Alzheimer's disease-associated EphA1 on Drosophila behaviour and neurophysiology

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease placing a great burden on people living with it, carers and society. Yet, the underlying patho-mechanisms remain unknown and treatments limited. To better understand the molecular changes associated with AD, genome-wide as...

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Main Authors: Edgar Buhl, Yoon A. Kim, Tom Parsons, Bangfu Zhu, Ismael Santa-Maria, Roger Lefort, James J.L. Hodge
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-08-01
Colecção:Neurobiology of Disease
Assuntos:
Alzheimer's disease
Ca2+ imaging
Circadian rhythms
Drosophila melanogaster
Electrophysiology
Eph/ephrin signalling
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0969996122001449
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