Neuroinflammatory Processes, A1 Astrocyte Activation and Protein Aggregation in the Retina of Alzheimer’s Disease Patients, Possible Biomarkers for Early Diagnosis

Alzheimer’s disease (AD), a primary cause of dementia in the aging population, is characterized by extracellular amyloid-beta peptides aggregation, intracellular deposits of hyperphosphorylated tau, neurodegeneration and glial activation in the brain. It is commonly thought that the lack of early di...

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Detalhes bibliográficos
Main Authors: Alfonso Grimaldi, Natalia Pediconi, Francesca Oieni, Rocco Pizzarelli, Maria Rosito, Maria Giubettini, Tiziana Santini, Cristina Limatola, Giancarlo Ruocco, Davide Ragozzino, Silvia Di Angelantonio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-09-01
Colecção:Frontiers in Neuroscience
Assuntos:
Alzheimer’s disease
microglia
astrocytes
retina
beta-amyloid
tau
Acesso em linha:https://www.frontiersin.org/article/10.3389/fnins.2019.00925/full
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