Attenuation of Scopolamine-Induced Amnesia via Cholinergic Modulation in Mice by Synthetic Curcumin Analogs

Alzheimer’s disease is an emerging health disorder associated with cognitive decline and memory loss. In this study, six curcumin analogs (<b>1a</b>–<b>1f</b>) were synthesized and screened for in vitro cholinesterase inhibitory potential. On the basis of promising results, t...

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Main Authors: Haya Hussain, Shujaat Ahmad, Syed Wadood Ali Shah, Abid Ullah, Niaz Ali, Mazen Almehmadi, Manzoor Ahmad, Atif Ali Khan Khalil, Syed Babar Jamal, Hanif Ahmad, Mustafa Halawi
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI AG 2022-04-01
Sraith:Molecules
Ábhair:
curcumin analogs
Alzheimer’s disease
amnesia
acetylcholinesterase
butyrylcholinesterase
docking
Rochtain Ar Líne:https://www.mdpi.com/1420-3049/27/8/2468
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