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Thyroid Cancer-Associated Mitochondrial DNA Mutation G3842A Promotes Tumorigenicity via ROS-Mediated ERK1/2 Activation

Mitochondrial DNA (mtDNA) mutations have been identified in various human cancers, including thyroid cancer. However, the relationship between mtDNA and thyroid cancer remains unclear. Previous studies by others and us strongly suggested that mtDNA mutations in complex I may participate in thyroid c...

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Bibliographische Detailangaben
Hauptverfasser: Sixi Chen, Xinzhu Bao, Hongzhi Chen, Manli Jia, Wen Li, Luyi Zhang, Runxiao Fan, Hezhi Fang, Liqin Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Limited 2022-01-01
Schriftenreihe:Oxidative Medicine and Cellular Longevity
Online Zugang:http://dx.doi.org/10.1155/2022/9982449
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