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Quantification of Factor H Mediated Self vs. Non-self Discrimination by Mathematical Modeling

The complement system is part of the innate immune system and plays an important role in the host defense against infectious pathogens. One of the main effects is the opsonization of foreign invaders and subsequent uptake by phagocytosis. Due to the continuous default basal level of active complemen...

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Main Authors: Alexander Tille, Teresa Lehnert, Peter F. Zipfel, Marc Thilo Figge
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-09-01
Colecção:Frontiers in Immunology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2020.01911/full
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