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Possible Role of Interaction between PPARα and Cyclophilin D in Cardioprotection of AMPK against In Vivo Ischemia-Reperfusion in Rats

Activated AMPK protects the heart from cardiac ischemia-reperfusion (IR) injury and is associated with inhibition of mitochondrial permeability transition pore (PTP) opening. On the other hand, pharmacological inhibition of the PTP reduces infarct size and improves cardiac function. However, it is u...

詳細記述

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書誌詳細
主要な著者: Giselle Barreto-Torres, Sabzali Javadov
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Limited 2016-01-01
シリーズ:PPAR Research
オンライン・アクセス:http://dx.doi.org/10.1155/2016/9282087
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