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Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis
Abstract Ectopic ceramide accumulation in insulin-responsive tissues contributes to the development of obesity and impairs insulin sensitivity. Moreover, pharmacological inhibition of serine palmitoyl transferase (SPT), the first enzyme essential for ceramide biosynthesis using myriocin in rodents r...
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Main Authors: | , , , , , , , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
Nature Portfolio
2022-05-01
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叢編: | Scientific Reports |
在線閱讀: | https://doi.org/10.1038/s41598-022-11219-3 |
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