Nodal Promotes the Self-Renewal of Human Colon Cancer Stem Cells via an Autocrine Manner through Smad2/3 Signaling Pathway

Colorectal cancer is one of the most common and fatal tumors. However, molecular mechanisms underlying carcinogenesis of colorectal cancer remain largely undefined. Here, we explored the expression and function of Nodal in colon cancer stem cells (CCSCs). Nodal and its receptors were present in nume...

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Huvudupphovsmän: Yuehua Gong, Ying Guo, Yanan Hai, Hao Yang, Yang Liu, Shi Yang, Zhenzhen Zhang, Meng Ma, Linhong Liu, Zheng Li, Zuping He
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Limited 2014-01-01
Serie:BioMed Research International
Länkar:http://dx.doi.org/10.1155/2014/364134
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