טוען...
FANCD1/BRCA2 plays predominant role in the repair of DNA damage induced by ACNU or TMZ.
Nimustine (ACNU) and temozolomide (TMZ) are DNA alkylating agents which are commonly used in chemotherapy for glioblastomas. ACNU is a DNA cross-linking agent and TMZ is a methylating agent. The therapeutic efficacy of these agents is limited by the development of resistance. In this work, the role...
שמור ב:
Main Authors: | , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
Public Library of Science (PLoS)
2011-05-01
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סדרה: | PLoS ONE |
גישה מקוונת: | http://europepmc.org/articles/PMC3090409?pdf=render |
תגים: |
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