Single-center study of Lynch syndrome screening in colorectal polyps

Abstract Background Lynch syndrome is the most common hereditary colorectal cancer syndrome, and adenoma is one of the important premalignant lesions to colorectal cancer in Lynch syndrome. The first objective of this study was to calculate the detection rate of Lynch syndrome in colorectal polyps b...

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Hlavní autoři: FangChao Zhu, Da Pan, Hui Zhang, Qiong Ye, PeiSong Xu, Jie Pan
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2019-03-01
Edice:Hereditary Cancer in Clinical Practice
Témata:
Lynch syndrome
Mismatch repair deficiency
Colorectal polyps
Immunohistochemistry
Genetic testing
Screening
On-line přístup:http://link.springer.com/article/10.1186/s13053-019-0108-6
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