Single-center study of Lynch syndrome screening in colorectal polyps

Abstract Background Lynch syndrome is the most common hereditary colorectal cancer syndrome, and adenoma is one of the important premalignant lesions to colorectal cancer in Lynch syndrome. The first objective of this study was to calculate the detection rate of Lynch syndrome in colorectal polyps b...

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Bibliographic Details
Main Authors: FangChao Zhu, Da Pan, Hui Zhang, Qiong Ye, PeiSong Xu, Jie Pan
Format: Artigo
Language:Inglês
Published: BMC 2019-03-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Lynch syndrome
Mismatch repair deficiency
Colorectal polyps
Immunohistochemistry
Genetic testing
Screening
Online Access:http://link.springer.com/article/10.1186/s13053-019-0108-6
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