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Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching.
Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial. However, the mechanisms underlying the effica...
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Autori principali: | , , , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Public Library of Science (PLoS)
2012-01-01
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Serie: | PLoS ONE |
Accesso online: | http://europepmc.org/articles/PMC3471825?pdf=render |
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