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Phylogenetic analysis of migration, differentiation, and class switching in B cells.
B cells undergo rapid mutation and selection for antibody binding affinity when producing antibodies capable of neutralizing pathogens. This evolutionary process can be intermixed with migration between tissues, differentiation between cellular subsets, and switching between functional isotypes. B c...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science (PLoS)
2022-04-01
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Colecção: | PLoS Computational Biology |
Acesso em linha: | https://doi.org/10.1371/journal.pcbi.1009885 |
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