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A chemical analog of curcumin as an improved inhibitor of amyloid Abeta oligomerization.

Amyloid-like plaques are characteristic lesions defining the neuropathology of Alzheimer's disease (AD). The size and density of these plaques are closely associated with cognitive decline. To combat this disease, the few therapies that are available rely on drugs that increase neurotransmissio...

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Main Authors: Robert A Orlando, Amanda M Gonzales, Robert E Royer, Lorraine M Deck, David L Vander Jagt
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science (PLoS) 2012-01-01
Sraith:PLoS ONE
Rochtain Ar Líne:http://europepmc.org/articles/PMC3307704?pdf=render
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