Mechanical loading of isolated cardiac muscle with a real‐time computed Windkessel model of the vasculature impedance

Abstract To date, the mechanical loads imposed on isolated cardiac muscle tissue in vitro have been oversimplified. Researchers typically applied loads that are time‐invariant, resulting in either isometric and auxotonic contractions, or flat‐topped (isotonic shortening) work‐loops. These contractio...

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Bibliographic Details
Main Authors: Amy S. Garrett, Toan Pham, Denis Loiselle, June‐Chiew Han, Andrew Taberner
Format: Artigo
Language:Inglês
Published: Wiley 2019-09-01
Series:Physiological Reports
Subjects:
Arterial Impedance
force‐length loop
heart muscle
mechanical work
Windkessel model
Online Access:https://doi.org/10.14814/phy2.14184
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