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Mechanical loading of isolated cardiac muscle with a real‐time computed Windkessel model of the vasculature impedance
Abstract To date, the mechanical loads imposed on isolated cardiac muscle tissue in vitro have been oversimplified. Researchers typically applied loads that are time‐invariant, resulting in either isometric and auxotonic contractions, or flat‐topped (isotonic shortening) work‐loops. These contractio...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Wiley
2019-09-01
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Serier: | Physiological Reports |
Fag: | |
Online adgang: | https://doi.org/10.14814/phy2.14184 |
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