Gut microbiome signatures linked to HIV-1 reservoir size and viremia control

Abstract Background The potential role of the gut microbiome as a predictor of immune-mediated HIV-1 control in the absence of antiretroviral therapy (ART) is still unknown. In the BCN02 clinical trial, which combined the MVA.HIVconsv immunogen with the latency-reversing agent romidepsin in early-AR...

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Main Authors: Alessandra Borgognone, Marc Noguera-Julian, Bruna Oriol, Laura Noël-Romas, Marta Ruiz-Riol, Yolanda Guillén, Mariona Parera, Maria Casadellà, Clara Duran, Maria C. Puertas, Francesc Català-Moll, Marlon De Leon, Samantha Knodel, Kenzie Birse, Christian Manzardo, José M. Miró, Bonaventura Clotet, Javier Martinez-Picado, José Moltó, Beatriz Mothe, Adam Burgener, Christian Brander, Roger Paredes, the BCN02 Study Group
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-04-01
Colecção:Microbiome
Assuntos:
HIV-1 post-treatment control
Gut microbiome
Therapeutic HIV-1 vaccine
Viral reservoir size
Microbiome-based predictive biomarker
Acesso em linha:https://doi.org/10.1186/s40168-022-01247-6
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