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Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions

Type 2 diabetes (T2D) is a very prevalent, multisystemic, chronic metabolic disorder closely related to atherosclerosis and cardiovascular diseases. It is characterised by mitochondrial dysfunction and the presence of oxidative stress. Metformin is one of the safest and most effective anti-hyperglyc...

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主要な著者: Nadezda Apostolova, Francesca Iannantuoni, Aleksandra Gruevska, Jordi Muntane, Milagros Rocha, Victor M. Victor
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020-07-01
シリーズ:Redox Biology
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オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2213231719315393
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