Winnie-<i>APC<sup>Min/+</sup></i> Mice: A Spontaneous Model of Colitis-Associated Colorectal Cancer Combining Genetics and Inflammation

(1) Background: Colorectal cancer (CRC) is among the best examples of the relationship between inflammation and increased cancer risk. (2) Methods: To examine the effects of spontaneous low-grade chronic inflammation on the pathogenesis of CRC, we developed a new murine model of colitis-associated c...

Full description

Saved in:
Bibliographic Details
Main Authors: Stefania De Santis, Giulio Verna, Grazia Serino, Raffaele Armentano, Elisabetta Cavalcanti, Marina Liso, Manuela Dicarlo, Sergio Coletta, Mauro Mastronardi, Antonio Lippolis, Angela Tafaro, Angelo Santino, Aldo Pinto, Pietro Campiglia, Alex Y. Huang, Fabio Cominelli, Theresa T. Pizarro, Marcello Chieppa
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
colorectal cancer
murine model
inflammation
Aberrant Crypt Foci
Online Access:https://www.mdpi.com/1422-0067/21/8/2972
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items