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The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity
<p>Abstract</p> <p>Background</p> <p>We characterized the biologic effects of a novel small molecule STAT3 pathway inhibitor that is derived from the natural product curcumin. We hypothesized this lead compound would specifically inhibit the STAT3 signaling pathway to i...
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Huvudupphovsmän: | , , , , , , , , , , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
BMC
2010-06-01
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Serie: | Molecular Cancer |
Länkar: | http://www.molecular-cancer.com/content/9/1/165 |
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