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The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity
<p>Abstract</p> <p>Background</p> <p>We characterized the biologic effects of a novel small molecule STAT3 pathway inhibitor that is derived from the natural product curcumin. We hypothesized this lead compound would specifically inhibit the STAT3 signaling pathway to i...
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Main Authors: | , , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
BMC
2010-06-01
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Serija: | Molecular Cancer |
Online dostop: | http://www.molecular-cancer.com/content/9/1/165 |
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