Sequence analysis of pfcrt and pfmdr1 genes and its association with chloroquine resistance in Southeast Indian Plasmodium falciparum isolates

Background: Due to the widespread resistance of Plasmodium falciparum to chloroquine drug, artemisinin-based combination therapy (ACT) has been recommended as the first-line treatment. This study aims to evaluate the extent of chloroquine resistance in P. falciparum infection after the introduction...

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Autori principali: Hiasindh Ashmi Antony, Sindhusuta Das, Subhash Chandra Parija, Sanghamitra Padhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2016-06-01
Serie:Genomics Data
Soggetti:
Drug resistance
Plasmodium falciparum
Chloroquine
pfcrt
pfmdr1
Accesso online:http://www.sciencedirect.com/science/article/pii/S2213596016300551
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