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Targeting Cytokine Signaling and Lymphocyte Traffic via Small Molecules in Inflammatory Bowel Disease: JAK Inhibitors and S1PR Agonists
The inflammatory Bowel diseases (IBDs) are a chronic, relapsing inflammatory diseases of the gastrointestinal tract with heterogeneous behavior and prognosis. The introduction of biological therapies including anti-TNF, anti-IL-12/23, and anti-integrins, has revolutionized the treatment of IBD, but...
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Main Authors: | , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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Frontiers Media S.A.
2019-03-01
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叢編: | Frontiers in Pharmacology |
主題: | |
在線閱讀: | https://www.frontiersin.org/article/10.3389/fphar.2019.00212/full |
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