Suppression of NLRP3 Inflammasome by Dihydroarteannuin via the HIF‐1α and JAK3/STAT3 Signaling Pathway Contributes to Attenuation of Collagen-Induced Arthritis in Mice

Dihydroarteannuin (DHA), the primary element of artemisinin extracted from the traditional Chinese herb Artemisia annua L., has been used in malaria treatment for a long time. Recently, many studies have indicated that DHA also exhibits potent anti-rheumatoid arthritis (RA) activity. In this study,...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Mingying Zhang, Danbin Wu, Jia Xu, Lijuan Liu, Wei Jiao, Jiahui Yu, Guangxing Chen
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Assuntos:
dihydroarteannuin
rheumatoid arthritis
traditional Chinese medicine
Jak3/Stat3
NLRP3
CIA mice
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fphar.2022.884881/full
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares