Anti-Tumor Effects of Peptide Therapeutic and Peptide Vaccine Antibody Co-targeting HER-1 and HER-2 in Esophageal Cancer (EC) and HER-1 and IGF-1R in Triple-Negative Breast Cancer (TNBC)

Despite the promise of targeted therapies, there remains an urgent need for effective treatment for esophageal cancer (EC) and triple-negative breast cancer (TNBC). Current FDA-approved drugs have significant problems of toxicity, safety, selectivity, efficacy and development of resistance. In this...

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Main Authors: Jay Overholser, Kristen Henkins Ambegaokar, Siobhan M. Eze, Eduardo Sanabria-Figueroa, Rita Nahta, Tanios Bekaii-Saab, Pravin T.P. Kaumaya
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2015-07-01
Colecção:Vaccines
Assuntos:
peptide mimics
epitopes
antibodies
immunogenicity
resistance
vaccine candidates
peptide vaccines
Acesso em linha:http://www.mdpi.com/2076-393X/3/3/519
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