HCT116 colorectal liver metastases exacerbate muscle wasting in a mouse model for the study of colorectal cancer cachexia

Colorectal cancer (CRC) is often accompanied by formation of liver metastases (LM) and skeletal muscle wasting, i.e. cachexia. Despite affecting the majority of CRC patients, cachexia remains underserved, understudied and uncured. Animal models for the study of CRC-induced cachexia, in particular mo...

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Detaylı Bibliyografya
Asıl Yazarlar: Joshua R. Huot, Leah J. Novinger, Fabrizio Pin, Andrea Bonetto
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists 2020-01-01
Seri Bilgileri:Disease Models & Mechanisms
Konular:
colorectal cancer
liver metastases
hct116
cachexia
stat3
skeletal muscle
Online Erişim:http://dmm.biologists.org/content/13/1/dmm043166
Etiketler: Etiketle
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