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Concurrent genome and epigenome editing by CRISPR-mediated sequence replacement
Abstract Background Recent advances in genome editing have facilitated the direct manipulation of not only the genome, but also the epigenome. Genome editing is typically performed by introducing a single CRISPR/Cas9-mediated double-strand break (DSB), followed by non-homologous end joining (NHEJ)-...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BMC
2019-11-01
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| Серии: | BMC Biology |
| Предметы: | |
| Online-ссылка: | http://link.springer.com/article/10.1186/s12915-019-0711-z |
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