Inhibition of Contractile Function in Human Joint Capsule Myofibroblasts by Targeting the TGF-β1 and PDGF Pathways.
Contractile myofibroblasts (MFs) accumulate in the joint capsules of patients suffering from posttraumatic joint stiffness. MF activation is controlled by a complex local network of growth factors and cytokines, ending in the increased production of extracellular matrix components followed by soft t...
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Autores principales: | , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Public Library of Science (PLoS)
2016-01-01
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Colección: | PLoS ONE |
Acceso en línea: | http://europepmc.org/articles/PMC4712129?pdf=render |
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