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Dual Oxidase Maturation Factor 1 Positively Regulates RANKL-Induced Osteoclastogenesis via Activating Reactive Oxygen Species and TRAF6-Mediated Signaling

Receptor activator of NF-κB ligand (RANKL) induces generation of intracellular reactive oxygen species (ROS), which act as second messengers in RANKL-mediated osteoclastogenesis. Dual oxidase maturation factor 1 (Duoxa1) has been associated with the maturation of ROS-generating enzymes including dua...

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Detalhes bibliográficos
Main Authors: Yoon-Hee Cheon, Chang Hoon Lee, Da Hye Jeong, Sung Chul Kwak, Soojin Kim, Myeung Su Lee, Ju-Young Kim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-09-01
Colecção:International Journal of Molecular Sciences
Assuntos:
ROS
Acesso em linha:https://www.mdpi.com/1422-0067/21/17/6416
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