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The Transcriptional Specificity of NF-κB Dimers Is Coded within the κB DNA Response Elements

Nuclear factor κB (NF-κB) regulates gene expression by binding to specific DNA elements, known collectively as κB sites, that are contained within the promoters/enhancers of target genes. We found that the identity of the central base pair (bp) of κB sites profoundly affects the transcriptional acti...

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Detalhes bibliográficos
Main Authors: Vivien Ya-Fan Wang, Wendy Huang, Masataka Asagiri, Nathanael Spann, Alexander Hoffmann, Christopher Glass, Gourisankar Ghosh
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012-10-01
Colecção:Cell Reports
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124712003154
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