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PRKDC promotes hepatitis B virus transcription through enhancing the binding of RNA Pol II to cccDNA
Abstract Hepatitis B virus infection remains a major health problem worldwide due to its high risk of liver failure and hepatocellular carcinoma. Covalently closed circular DNA (cccDNA), which is present as an individual minichromosome, serves as the template for transcription of all viral RNAs and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2022-04-01
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| Colecção: | Cell Death and Disease |
| Acesso em linha: | https://doi.org/10.1038/s41419-022-04852-3 |
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