Autophagy suppression of trophoblast cells induces pregnancy loss by activating decidual NK cytotoxicity and inhibiting trophoblast invasion

Abstract Background The crosstalk between trophoblast cells and decidual NK cells plays an important role in the establishment and maintenance of normal pregnancy. Recent studies reported that autophagy can induce immune tolerance at the maternal fetal interface, while the mechanism remains unclear....

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Auteurs principaux: Hai-Xia Tan, Shao-Liang Yang, Ming-Qing Li, Hai-Yan Wang
Format: Artigo
Langue:Inglês
Publié: BMC 2020-05-01
Collection:Cell Communication and Signaling
Sujets:
RSA
Trophoblast autophagy
NK cell
IGF-2
PEG10
Accès en ligne:http://link.springer.com/article/10.1186/s12964-020-00579-w
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