Frequency-Dependent Properties of the Hyperpolarization-Activated Cation Current, I<sub>f</sub>, in Adult Mouse Heart Primary Pacemaker Myocytes

A number of distinct electrophysiological mechanisms that modulate the myogenic spontaneous pacemaker activity in the sinoatrial node (SAN) of the mammalian heart have been investigated extensively. There is agreement that several (3 or 4) different transmembrane ionic current changes (referred to a...

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Bibliographic Details
Main Authors: Wei Hu, Robert B. Clark, Wayne R. Giles, Colleen Kondo, Henggui Zhang
Format: Artigo
Language:Inglês
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
mouse heart
sino-atrial node
SAN
spontaneous pacemaker activity
pacemaker depolarization
hyperpolarization-activated current
Online Access:https://www.mdpi.com/1422-0067/23/8/4299
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