Wnt Binding Affinity Prediction for Putative Frizzled-Type Cysteine-Rich Domains

Several proteins other than the frizzled receptors (Fzd) and the secreted Frizzled-related proteins (sFRP) contain Fzd-type cysteine-rich domains (CRD). We have termed these domains “putative Fzd-type CRDs”, as the relevance of Wnt signalling in the majority of these is unknown;...

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Hauptverfasser: Mark Agostino, Sebastian Öther-Gee Pohl
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2019-08-01
Schriftenreihe:International Journal of Molecular Sciences
Schlagworte:
Wnt signalling
Frizzled
smoothened
cysteine-rich domain
protein‒protein interactions
Online Zugang:https://www.mdpi.com/1422-0067/20/17/4168
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