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TFEB Probably Involved in Midazolam-Disturbed Lysosomal Homeostasis and Its Induced β-Amyloid Accumulation
Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases, and β-amyloid (Aβ) plays a leading role in the pathogenesis of AD. The transcription factor EB (TFEB), a main regulating factor of autophagy and lysosome biosynthesis, is involved in the pathogenesis of AD by regulating a...
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主要な著者: | , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Frontiers Media S.A.
2019-05-01
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シリーズ: | Frontiers in Human Neuroscience |
主題: | |
オンライン・アクセス: | https://www.frontiersin.org/article/10.3389/fnhum.2019.00108/full |
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