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TFEB Probably Involved in Midazolam-Disturbed Lysosomal Homeostasis and Its Induced β-Amyloid Accumulation

Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases, and β-amyloid (Aβ) plays a leading role in the pathogenesis of AD. The transcription factor EB (TFEB), a main regulating factor of autophagy and lysosome biosynthesis, is involved in the pathogenesis of AD by regulating a...

詳細記述

保存先:
書誌詳細
主要な著者: Dan Cheng, Qilian Tan, Qianyun Zhu, Jiqian Zhang, Xiaoyu Han, Panpan Fang, Weilin Jin, Xuesheng Liu
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019-05-01
シリーズ:Frontiers in Human Neuroscience
主題:
オンライン・アクセス:https://www.frontiersin.org/article/10.3389/fnhum.2019.00108/full
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