Receptor-Mediated Vascular Smooth Muscle Migration Induced by LPA Involves p38 Mitogen-Activated Protein Kinase Pathway Activation

Lysophosphatidic acid (LPA), a naturally occurring glycerophospholipid, can evoke various biological responses, including cell migration, proliferation and survival, via activation of G protein-coupled receptors (GPCRs). However, the role of LPA receptors and details of LPA signaling in migration ar...

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Hauptverfasser: Zhi-Jun Zhang, Zhi-Bin Zhou, Jian-Ping Niu
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2009-07-01
Schriftenreihe:International Journal of Molecular Sciences
Schlagworte:
lysophosphatidic acid
receptor
vascular smooth muscle cell
migration
p38 mitogen-activated protein kinase
Online Zugang:http://www.mdpi.com/1422-0067/10/7/3194/
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