SB203580, a p38MAPK inhibitor, attenuates olfactory dysfunction by inhibiting OSN apoptosis in AR mice (activation and involvement of the p38 mitogen‐activated protein kinase in olfactory sensory neuronal apoptosis of OVA‐induced allergic rhinitis)

Abstract Objective This study aimed to investigate the effect of the p38 mitogen‐activated protein kinase (p38MAPK) signaling pathway on olfactory mucosa function and apoptosis of olfactory sensory neurons (OSNs) in an allergic rhinitis (AR) mouse model. Method Fifty‐five BALB/c mice were used to es...

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Main Authors: Xian Gao, Na Li, Jisheng Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2019-06-01
Colecção:Brain and Behavior
Assuntos:
allergic rhinitis (AR)
apoptosis
mouse model
olfaction dysfunction
olfactory sensory neuron (OSN)
p38 mitogen‐activated protein kinase (p38MAPK)
Acesso em linha:https://doi.org/10.1002/brb3.1295
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