Roles for the IKK-Related Kinases TBK1 and IKKε in Cancer

While primarily studied for their roles in innate immune response, the IκB kinase (IKK)-related kinases TANK-binding kinase 1 (TBK1) and IKKε also promote the oncogenic phenotype in a variety of cancers. Additionally, several substrates of these kinases control proliferation, a...

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Autori principali: Joel K. Durand, Qing Zhang, Albert S. Baldwin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2018-09-01
Serie:Cells
Soggetti:
TBK1
IKKε
innate immunity
cancer signaling
autophagy
KRAS
Accesso online:http://www.mdpi.com/2073-4409/7/9/139
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