Roles for the IKK-Related Kinases TBK1 and IKKε in Cancer

While primarily studied for their roles in innate immune response, the IκB kinase (IKK)-related kinases TANK-binding kinase 1 (TBK1) and IKKε also promote the oncogenic phenotype in a variety of cancers. Additionally, several substrates of these kinases control proliferation, a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Joel K. Durand, Qing Zhang, Albert S. Baldwin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2018-09-01
Cyfres:Cells
Pynciau:
TBK1
IKKε
innate immunity
cancer signaling
autophagy
KRAS
Mynediad Ar-lein:http://www.mdpi.com/2073-4409/7/9/139
Tagiau: Ychwanegu Tag
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