Roles for the IKK-Related Kinases TBK1 and IKKε in Cancer

While primarily studied for their roles in innate immune response, the IκB kinase (IKK)-related kinases TANK-binding kinase 1 (TBK1) and IKKε also promote the oncogenic phenotype in a variety of cancers. Additionally, several substrates of these kinases control proliferation, a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Joel K. Durand, Qing Zhang, Albert S. Baldwin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2018-09-01
Saila:Cells
Gaiak:
TBK1
IKKε
innate immunity
cancer signaling
autophagy
KRAS
Sarrera elektronikoa:http://www.mdpi.com/2073-4409/7/9/139
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