Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle

<p>Abstract</p> <p>Background</p> <p>The expression of PDK4 is elevated by diabetes, fasting and other conditions associated with the switch from the utilization of glucose to fatty acids as an energy source. It is previously shown that peroxisome proliferator-activated...

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Main Authors: Rinnankoski-Tuikka Rita, Silvennoinen Mika, Torvinen Sira, Hulmi Juha J, Lehti Maarit, Kivelä Riikka, Reunanen Hilkka, Kainulainen Heikki
Format: Artigo
Jezik:Inglês
Izdano: BMC 2012-06-01
Serija:Nutrition & Metabolism
Teme:
Skeletal muscle
Mitochondria
Lipids
Glucose
Fuel switching
Online dostop:http://www.nutritionandmetabolism.com/content/9/1/53
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