Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle

<p>Abstract</p> <p>Background</p> <p>The expression of PDK4 is elevated by diabetes, fasting and other conditions associated with the switch from the utilization of glucose to fatty acids as an energy source. It is previously shown that peroxisome proliferator-activated...

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Bibliographic Details
Main Authors: Rinnankoski-Tuikka Rita, Silvennoinen Mika, Torvinen Sira, Hulmi Juha J, Lehti Maarit, Kivelä Riikka, Reunanen Hilkka, Kainulainen Heikki
Format: Artigo
Language:Inglês
Published: BMC 2012-06-01
Series:Nutrition & Metabolism
Subjects:
Skeletal muscle
Mitochondria
Lipids
Glucose
Fuel switching
Online Access:http://www.nutritionandmetabolism.com/content/9/1/53
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