Phase II trial of Modified Vaccinia Ankara (MVA) virus expressing 5T4 and high dose Interleukin-2 (IL-2) in patients with metastatic renal cell carcinoma

<p>Abstract</p> <p>Background</p> <p>Interleukin-2 (IL-2) induces durable objective responses in a small cohort of patients with metastatic renal cell carcinoma (RCC) but the antigen(s) responsible for tumor rejection are not known. 5T4 is a non-secreted membrane glycop...

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Detalhes bibliográficos
Main Authors: Mitcham Josephine, DeRaffele Gail, Moroziewicz Dorota, Shingler William H, Kim Dae, Sherman William, Taback Bret, Kaufman Howard L, Carroll Miles W, Harrop Richard, Naylor Stuart, Kim-Schulze Seunghee
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2009-01-01
Colecção:Journal of Translational Medicine
Acesso em linha:http://www.translational-medicine.com/content/7/1/2
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