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Post-translational Modifications of the p53 Protein and the Impact in Alzheimer’s Disease: A Review of the Literature

Our understanding of Alzheimer’s disease (AD) pathogenesis has developed with several hypotheses over the last 40 years, including the Amyloid and Tau hypotheses. More recently, the p53 protein, well-known as a genome guardian, has gained attention for its potential role in the early evolution of AD...

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Hlavní autoři: James S. Clark, Rakez Kayed, Giulia Abate, Daniela Uberti, Paul Kinnon, Simona Piccirella
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-04-01
Edice:Frontiers in Aging Neuroscience
Témata:
p53
On-line přístup:https://www.frontiersin.org/articles/10.3389/fnagi.2022.835288/full
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