DISSOLUTION PROFILE STUDY OF EXTENDED RELEASE VALPROIC ACID DRUG PRODUCTS FROM DIFFERENT MANUFACTURERS

Dissolution profiles of four extended release valproic acid tablets from different manufacturers and granules Depakine® Chronosphere 500 mg were studied in three dissolution media: pH 1.2; 4.5, 6.8 (quality control medium). Dissolution profiles similarity for tablets was approved and more rapid diss...

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Detalhes bibliográficos
Main Authors: D. Yu. Grebenkin, E. D. Ustinova, S. Yu. Gorbacheva, A. K. Faeva, V. I. Kazey, A. V. Ryabova
Formato: Artigo
Idioma:Russo
Publicado em: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Colecção:Разработка и регистрация лекарственных средств
Assuntos:
valproic acid
dissolution profile testing
hplc
Acesso em linha:https://www.pharmjournal.ru/jour/article/view/590
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