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DISSOLUTION PROFILE STUDY FOR INNOVATION ANTI-RETROVIRAL DRUG PRODUCT NIKAVIR® AND ITS FIXED COMBINATION WITH LAMIVUDINE (PHOSPHALADINE®)

Biopharmaceutical solubility was experimentally determined for innovation anti-retroviral API phosphazide (Nikavir®) which was classified as BCS Class 3 drug. Dissolution profile test for Nikavir® 200 mg and 400 mg in three media pH 1.2, 4.5, 6.8 was conducted, and equivalence for both dosages was s...

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Detalhes bibliográficos
Main Authors: I. E. Shohin, Yu. V. Medvedev, T. N. Komarov, O. V. Klimova, B. V. Brovchenko
Formato: Artigo
Idioma:Russo
Publicado em: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Colecção:Разработка и регистрация лекарственных средств
Assuntos:
bcs
Acesso em linha:https://www.pharmjournal.ru/jour/article/view/94
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