Mitochondrial – nuclear genetic interaction modulates whole body metabolism, adiposity and gene expression in vivoResearch in context

We hypothesized that changes in the mitochondrial DNA (mtDNA) would significantly influence whole body metabolism, adiposity and gene expression in response to diet. Because it is not feasible to directly test these predictions in humans we used Mitochondrial-Nuclear eXchange mice, which have recipr...

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Библиографические подробности
Главные авторы: Kimberly J. Dunham-Snary, Michael W. Sandel, Melissa J. Sammy, David G. Westbrook, Rui Xiao, Ryan J. McMonigle, William F. Ratcliffe, Arthur Penn, Martin E. Young, Scott W. Ballinger
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2018-10-01
Серии:EBioMedicine
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S2352396418303323
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