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Mitochondrial – nuclear genetic interaction modulates whole body metabolism, adiposity and gene expression in vivoResearch in context

We hypothesized that changes in the mitochondrial DNA (mtDNA) would significantly influence whole body metabolism, adiposity and gene expression in response to diet. Because it is not feasible to directly test these predictions in humans we used Mitochondrial-Nuclear eXchange mice, which have recipr...

詳細記述

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書誌詳細
主要な著者: Kimberly J. Dunham-Snary, Michael W. Sandel, Melissa J. Sammy, David G. Westbrook, Rui Xiao, Ryan J. McMonigle, William F. Ratcliffe, Arthur Penn, Martin E. Young, Scott W. Ballinger
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2018-10-01
シリーズ:EBioMedicine
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2352396418303323
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